Refer to https://developers.facebook.com/docs/apps/review/login-permissions#manage-pages and https://developers.facebook.com/docs/apps/review/feature#reference-PAGES_ACCESS for details.  Studies in adult rats found that oxybenzones do not have effects on the uterus. , Cancer: The California EPA’s Proposition 65 list identifies benzophenone as a possible human carcinogen. Safety Measures/Side Effects of Benzophenone-3: There are several suspected dangers associated with benzophenone … Show transcribed image text. What is the lowest possible melting point for ice that could be obtained considering the solubility of NaCl in water? May cause respiratory and digestive tract irritation.  Oxybenzone can permeate across the skin and accumulate in blood, the kidneys and the liver, and may be toxic to liver cells. ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.  In addition, BP4 interferes with the expression of genes that control sex hormones in zebrafish, a species widely used to measure endocrine activity of substances. 2.  However, studies of benzophenone in juvenile female rats conclude that benzophenone s not estrogenic itself, but may become estrogenic when it is metabolized by the body into other chemicals (for instance, the benzophenone metabolite p-hydrosybenzophenone is estrogenic). 1. Oxybenzone is used as an ultraviolet light absorber and stabilizer especially in plastics and sunscreen agents. , Organ System Toxicity: The European Food Safety Authority (EFSA) classifies benzophenone as a known toxicant because benzophenone can cause liver hypertrophy in the rat at lower doses. Reported as not meeting GHS hazard criteria by 2153 of 2614 companies. , Benzophenone 4 (BP4) has low levels of estrogenic activity in studies of cells, but this activity did not lead to changes in body weight and length in fish, which is a sensitive measure of estrogen exposure.  Other studies suggest that use can lead photoallergy, allergic contact dermatitis and facial erythema. Define the following terms clearly and concisely.  Benzophenone and oxybenzone are also used in nail polish, and lip balm.  Derivatives of benzophenones such as BP2 and oxybenzone (BP3) are used in sunscreens. Question: List The CAS Number And Hazards Associated With Benzophenone, C_13H_10O. View desktop site, 1. 3. , Endocrine disruption: Benzophenone and its derived chemicals may influence the endocrine system.  Experimental studies suggest benzophenone may lead to several kinds of tumors.  Oxybenzone can permeate across the skin and accumulate in blood, the kidneys and the liver, and may be toxic to liver cells. | Some studies indicate that the benzophenone derivative, oxybenzone, can elicit strong anti-androgenic activities in a human breast carcinoma cell line MDA-kb2.  Biphenyl is a benzenoid aromatic compound that consists of two benzene rings connected by a single covalent bond. Sodium borohydride is a white to grayish crystalline powder. For more detailed information, please visit ECHA C&L website.   These chemicals are linked to cancer, endocrine disruption, and organ system toxicity. The toxicological properties of this material have not been fully investigated. It is decomposed by water to form sodium hydroxide, a corrosive material, and hydrogen, a flammable gas.The heat of this reaction may be … This Fact Sheet is a summary of available information regarding the health hazards …  Other research suggests oxybenzone has estrogenic activity, as indicated by studies of estrogen-sensitive MCF-7 breast cancer cell lines, but other studies found less estrogenic activity. In personal care products, benzophenone is used as a fragrance enhancer or to prevent products such as soaps from losing scents and colors in the presence of UV light. Formerly used as a … BP2 affects ovaries of female fish and testes of male fish, and also reduces production of eggs and sperm. Caution! May cause eye and skin irritation. For this reason, benzophenone-3 is most often used in conjunction with other sunscreen agents. List the CAS number and hazards associated with benzophenone, C_13 H_18 O. Error: (#10) This endpoint requires the 'manage_pages' or 'pages_read_user_content' permission or the 'Page Public Content Access' feature. Molality K_f Solute Salt, NaCl, Has A Solubility Of 35.7 G Per 100 G Of Water At 0 Degree C. The Solubility Of Salt In Water Does Not Vary Appreciably With Temperature.  BP2, BP8 and THB stimulate the proliferation (growth and multiplication) of MCF-7 cells, which are used to test for estrogenic activity. 1.  Benzophenone and oxybenzone are also used in nail polish, and lip balm. Some studies indicate that benzophenone has little estrogenic activity. Question: What Is The CAS Number And Hazards Associated With Benzophenone, CHoO? The evidence linking benzophenone and different derivatives to endocrine disruption is complex, and research suggests that different benzophenones have different endocrine effects.  Studies of estrogenic activity and reproductive effects of oxybenzone found that oxybenzone can alter reproductive endpoints in fish species.  BP2, BP8 and THB stimulate the proliferation (growth and multiplication) of MCF-7 cells, which are used to test for estrogenic activity. Choose sunscreens that rely on non-nanoized zinc oxide or titanium dioxide. Salt, NaCl, has a solubility of 35.7 g per 100 g of water at 0 °C. © 2020 Campaign for Safe Cosmetics, a project of, http://cosmeticsinfo.org/ingredient/benzophenone-1, http://ec.europa.eu/consumers/cosmetics/cosing/index.cfm?fuseaction=search.details_v2&id=28809 July 10, http://monographs.iarc.fr/ENG/Monographs/vol101/mono101-007.pdf, https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr533.pdf, http://www.ewg.org/skindeep/ingredient/700684/BENZOPHENONE/, http://www.ewg.org/skindeep/ingredient/704372/OXYBENZONE/, https://oehha.ca.gov/proposition-65/crnr/chemicals-listed-known-state-cause-cancer-or-reproductive-toxicity, http://ec.europa.eu/environment/archives/docum/pdf/bkh_annex_13.pdf, http://www.efsa.europa.eu/en/efsajournal/pub/1104. of benzophenone = 119-61-9 Potential hazards associated with benzophenone are irritant when comes in contact with skin, eyes or upon inhalation.  Oxybenzone concentrations vary considerably by season, and may be especially high in areas where sunscreens are heavily used in specific months. Irritation: Studies show that sunscreen products formulated with concentrations of up to 6 percent of oxybenzone rarely led to allergic reactions—in fact, only about 7/10,000 people had an allergic reaction in one study. 119-61-9 Benzophenone 100.0 204-337-6 Section 3 - Hazards Identification EMERGENCY OVERVIEW Appearance: white solid. The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Benzophenone is persistent, bioaccumulative and toxic (PBT). Endocrine disruption: Benzophenone and its derived chemicals may influence the endocrine system.  The European Commission on Endocrine Disruption has determined that there is not yet sufficient evidence that benzophenone itself is a human endocrine disruptor.